adducin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
cell morphogenesis [GO:0000902],
in utero embryonic development [GO:0001701],
cell volume homeostasis [GO:0006884],
hemoglobin metabolic process [GO:0020027],
actin cytoskeleton organization [GO:0030036],
erythrocyte differentiation [GO:0030218],
positive regulation of protein binding [GO:0032092],
multicellular organism growth [GO:0035264],
IRE1-mediated unfolded protein response [GO:0036498],
homeostasis of number of cells within a tissue [GO:0048873],
barbed-end actin filament capping [GO:0051016],
actin filament bundle assembly [GO:0051017],
transmembrane transport [GO:0055085],
cellular response to calcium ion [GO:0071277],
positive regulation of establishment of endothelial barrier [GO:1903142],
positive regulation of adherens junction organization [GO:1903393],
negative regulation of actin filament polymerization [GO:0030837],
positive regulation of angiogenesis [GO:0045766],
positive regulation of endocytosis [GO:0045807],
cellular response to retinoic acid [GO:0071300],

Molecular Function:
RNA binding [GO:0003723],
actin binding [GO:0003779],
structural molecule activity [GO:0005198],
structural constituent of cytoskeleton [GO:0005200],
calmodulin binding [GO:0005516],
transcription factor binding [GO:0008134],
spectrin binding [GO:0030507],
protein homodimerization activity [GO:0042803],
cadherin binding [GO:0045296],
protein heterodimerization activity [GO:0046982],
actin filament binding [GO:0051015],
T cell receptor binding [GO:0042608],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
adherens junction [GO:0005912],
focal adhesion [GO:0005925],
F-actin capping protein complex [GO:0008290],
postsynaptic density [GO:0014069],
nuclear body [GO:0016604],
plasma membrane raft [GO:0044853],
membrane [GO:0016020],
dendrite [GO:0030425],
dendritic spine [GO:0043197],
synapse [GO:0045202],
perinuclear region of cytoplasm [GO:0048471],