ADCYAP receptor type I

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188],
activation of phospholipase C activity [GO:0007202],
spermatogenesis [GO:0007283],
positive regulation of calcium ion transport into cytosol [GO:0010524],
cAMP-mediated signaling [GO:0019933],
cell differentiation [GO:0030154],
response to estradiol [GO:0032355],
multicellular organismal response to stress [GO:0033555],
positive regulation of cAMP-mediated signaling [GO:0043950],
response to ethanol [GO:0045471],
development of primary female sexual characteristics [GO:0046545],
positive regulation of small GTPase mediated signal transduction [GO:0051057],
negative regulation of cell death [GO:0060548],
positive regulation of inositol phosphate biosynthetic process [GO:0060732],
signal transduction [GO:0007165],
multicellular organism development [GO:0007275],

Molecular Function:
vasoactive intestinal polypeptide receptor activity [GO:0004999],
protein binding [GO:0005515],
adenylate cyclase binding [GO:0008179],
G-protein coupled peptide receptor activity [GO:0008528],
peptide hormone binding [GO:0017046],
ADP-ribosylation factor binding [GO:0030306],
signaling receptor activity [GO:0038023],
neuropeptide binding [GO:0042923],
transmembrane signaling receptor activity [GO:0004888],
G-protein coupled receptor activity [GO:0004930],

Cellular Component:
endosome [GO:0005768],
rough endoplasmic reticulum [GO:0005791],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
caveola [GO:0005901],
bicellular tight junction [GO:0005923],
cell surface [GO:0009986],
neuron projection [GO:0043005],
intracellular membrane-bounded organelle [GO:0043231],
receptor complex [GO:0043235],
cytoplasm [GO:0005737],
membrane [GO:0016020],
integral component of membrane [GO:0016021],