centromere protein K

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
30987592 MCF7 Breast Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
mitotic sister chromatid segregation [GO:0000070],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
kinetochore assembly [GO:0051382],
CENP-A containing nucleosome assembly [GO:0034080],

Molecular Function:
protein binding [GO:0005515],

Cellular Component:
chromosome, centromeric region [GO:0000775],
kinetochore [GO:0000776],
condensed nuclear chromosome inner kinetochore [GO:0000941],
nucleus [GO:0005634],
chromosome [GO:0005694],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],