ADCY2
adenylate cyclase 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
31945125 | Primary astrocytes derived from brain | Human | YES |
GO terms:
Biological Process:
renal water homeostasis [GO:0003091],
cAMP biosynthetic process [GO:0006171],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
activation of adenylate cyclase activity [GO:0007190],
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193],
cAMP-mediated signaling [GO:0019933],
activation of protein kinase A activity [GO:0034199],
cellular response to glucagon stimulus [GO:0071377],
cellular response to forskolin [GO:1904322],
cyclic nucleotide biosynthetic process [GO:0009190],
intracellular signal transduction [GO:0035556],
Molecular Function:
magnesium ion binding [GO:0000287],
adenylate cyclase activity [GO:0004016],
ATP binding [GO:0005524],
adenylate cyclase binding [GO:0008179],
manganese ion binding [GO:0030145],
nucleotide binding [GO:0000166],
lyase activity [GO:0016829],
phosphorus-oxygen lyase activity [GO:0016849],
G-protein beta/gamma-subunit complex binding [GO:0031683],
metal ion binding [GO:0046872],
Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
membrane [GO:0016020],
dendrite [GO:0030425],
membrane raft [GO:0045121],
integral component of membrane [GO:0016021],
macromolecular complex [GO:0032991],