ADAT3

adenosine deaminase tRNA specific 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
tRNA wobble adenosine to inosine editing [GO:0002100],
tRNA modification [GO:0006400],

Molecular Function:
metal ion binding [GO:0046872],
tRNA-specific adenosine-34 deaminase activity [GO:0052717],

Cellular Component:
nucleoplasm [GO:0005654],
tRNA-specific adenosine-34 deaminase complex [GO:0052718],