ADAP1

ArfGAP with dual PH domains 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell surface receptor signaling pathway [GO:0007166],
regulation of GTPase activity [GO:0043087],
positive regulation of GTPase activity [GO:0043547],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
inositol 1,3,4,5 tetrakisphosphate binding [GO:0043533],
metal ion binding [GO:0046872],
phosphatidylinositol bisphosphate binding [GO:1902936],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
intracellular membrane-bounded organelle [GO:0043231],