ADAMTSL4

ADAMTS like 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
epithelial cell development [GO:0002064],
proteolysis [GO:0006508],
apoptotic process [GO:0006915],
extracellular matrix organization [GO:0030198],
positive regulation of apoptotic process [GO:0043065],

Molecular Function:
protease binding [GO:0002020],
metalloendopeptidase activity [GO:0004222],
protein binding [GO:0005515],
peptidase activity [GO:0008233],

Cellular Component:
interstitial matrix [GO:0005614],
endoplasmic reticulum lumen [GO:0005788],
extracellular matrix [GO:0031012],
extracellular region [GO:0005576],