ADAMTS7

ADAM metallopeptidase with thrombospondin type 1 motif 7

Link to human ortholog
Link to mouse ortholog

Status in senescence: Up-regulated
Pubmed ID	Cell line	Tissue	Source	High-throughput
29321003	Primary bronchial epithelial cells derived from lung		Human	YES
29548335	Li Fraumeni		Human	YES
31945125	Primary astrocytes derived from brain		Human	YES

Biological Process:
extracellular matrix organization [GO:0030198],
negative regulation of chondrocyte differentiation [GO:0032331],
proteolysis involved in cellular protein catabolic process [GO:0051603],
cellular response to interleukin-1 [GO:0071347],
cellular response to tumor necrosis factor [GO:0071356],
cellular response to BMP stimulus [GO:0071773],
proteolysis [GO:0006508],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
protein binding [GO:0005515],
metallopeptidase activity [GO:0008237],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular region [GO:0005576],
endoplasmic reticulum lumen [GO:0005788],
cell surface [GO:0009986],
extracellular matrix [GO:0031012],