ADAM metallopeptidase with thrombospondin type 1 motif 6

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
cardiac septum development [GO:0003279],
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
aorta development [GO:0035904],
coronary vasculature development [GO:0060976],
heart development [GO:0007507],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
metallopeptidase activity [GO:0008237],
metal ion binding [GO:0046872],
molecular_function [GO:0003674],

Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],
cellular_component [GO:0005575],