ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 32029712 | Primary synovial fibroblast | Human | YES | |
| 33296652 | heart | heart | Human | NO |
GO terms:
Biological Process:
spermatogenesis [GO:0007283],
protein processing [GO:0016485],
extracellular matrix organization [GO:0030198],
collagen fibril organization [GO:0030199],
lung development [GO:0030324],
collagen catabolic process [GO:0030574],
skin development [GO:0043588],
proteolysis [GO:0006508],
Molecular Function:
metalloendopeptidase activity [GO:0004222],
metallopeptidase activity [GO:0008237],
zinc ion binding [GO:0008270],
peptidase activity [GO:0008233],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],
Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],