ADAM metallopeptidase with thrombospondin type 1 motif 17

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
biological_process [GO:0008150],

Molecular Function:
nucleic acid binding [GO:0003676],
metalloendopeptidase activity [GO:0004222],
metal ion binding [GO:0046872],
molecular_function [GO:0003674],

Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],