ADAM metallopeptidase with thrombospondin type 1 motif 16

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
branching involved in ureteric bud morphogenesis [GO:0001658],
regulation of systemic arterial blood pressure [GO:0003073],
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
male gamete generation [GO:0048232],
regulation of cilium assembly [GO:1902017],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
metal ion binding [GO:0046872],
molecular_function [GO:0003674],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],