ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
| 32029712 | Primary synovial fibroblast | Human | YES | |
GO terms:
Biological Process:
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
Molecular Function:
metalloendopeptidase activity [GO:0004222],
heparin binding [GO:0008201],
zinc ion binding [GO:0008270],
extracellular matrix binding [GO:0050840],
endopeptidase activity [GO:0004175],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],
Cellular Component:
extracellular space [GO:0005615],
cell surface [GO:0009986],
extracellular matrix [GO:0031012],
extracellular region [GO:0005576],