cell death inducing p53 target 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
apoptotic process [GO:0006915],
tumor necrosis factor-mediated signaling pathway [GO:0033209],
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771],

Molecular Function:
molecular_function [GO:0003674],
protein binding [GO:0005515],
metal ion binding [GO:0046872],

Cellular Component:
nucleus [GO:0005634],
cytoplasmic side of late endosome membrane [GO:0098560],
cytoplasmic side of lysosomal membrane [GO:0098574],
lysosome [GO:0005764],
endosome [GO:0005768],
membrane [GO:0016020],