ADAM metallopeptidase with thrombospondin type 1 motif 14

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
extracellular matrix organization [GO:0030198],
collagen fibril organization [GO:0030199],
collagen catabolic process [GO:0030574],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],

Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],