ADAMTS12

ADAM metallopeptidase with thrombospondin type 1 motif 12

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

GO terms:

Biological Process:
cell-matrix adhesion [GO:0007160],
cell migration [GO:0016477],
proteoglycan catabolic process [GO:0030167],
extracellular matrix organization [GO:0030198],
negative regulation of chondrocyte differentiation [GO:0032331],
regulation of inflammatory response [GO:0050727],
proteolysis involved in cellular protein catabolic process [GO:0051603],
cellular response to interleukin-1 [GO:0071347],
cellular response to tumor necrosis factor [GO:0071356],
cellular response to BMP stimulus [GO:0071773],
regulation of endothelial tube morphogenesis [GO:1901509],
negative regulation of hepatocyte growth factor receptor signaling pathway [GO:1902203],
negative regulation of cellular response to vascular endothelial growth factor stimulus [GO:1902548],
negative regulation of cellular response to hepatocyte growth factor stimulus [GO:2001113],
proteolysis [GO:0006508],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],

Cellular Component:
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],