ADAM metallopeptidase with thrombospondin type 1 motif 10

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
biological_process [GO:0008150],
extracellular matrix organization [GO:0030198],

Molecular Function:
molecular_function [GO:0003674],
metalloendopeptidase activity [GO:0004222],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],

Cellular Component:
microfibril [GO:0001527],
extracellular matrix [GO:0031012],
extracellular region [GO:0005576],