CDC42 binding protein kinase alpha

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
protein phosphorylation [GO:0006468],
cell migration [GO:0016477],
peptidyl-threonine phosphorylation [GO:0018107],
actomyosin structure organization [GO:0031032],
actin cytoskeleton reorganization [GO:0031532],
intracellular signal transduction [GO:0035556],
microtubule cytoskeleton organization [GO:0000226],
cytoskeleton organization [GO:0007010],
nuclear migration [GO:0007097],
phosphorylation [GO:0016310],
actin cytoskeleton organization [GO:0030036],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
magnesium ion binding [GO:0000287],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
ATP binding [GO:0005524],
identical protein binding [GO:0042802],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
cell-cell junction [GO:0005911],
lamellipodium [GO:0030027],
cell leading edge [GO:0031252],
actomyosin [GO:0042641],
extracellular exosome [GO:0070062],
cell projection [GO:0042995],