ADAM23
ADAM metallopeptidase domain 23
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 31945054 | IMR-90 | Human | YES | |
GO terms:
Biological Process:
proteolysis [GO:0006508],
cell adhesion [GO:0007155],
central nervous system development [GO:0007417],
cellular response to leukemia inhibitory factor [GO:1990830],
Molecular Function:
metalloendopeptidase activity [GO:0004222],
integrin binding [GO:0005178],
protein binding [GO:0005515],
metallopeptidase activity [GO:0008237],
Cellular Component:
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
glutamatergic synapse [GO:0098978],
integral component of presynaptic membrane [GO:0099056],
membrane [GO:0016020],
integral component of membrane [GO:0016021],