CD38

CD38 molecule

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31551807 H9c2(2-1) Rat NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30535454 NPC, 5-8F Human NO

GO terms:

Biological Process:
response to hypoxia [GO:0001666],
signal transduction [GO:0007165],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
female pregnancy [GO:0007565],
negative regulation of neuron projection development [GO:0010977],
artery smooth muscle contraction [GO:0014824],
NAD metabolic process [GO:0019674],
positive regulation of cell growth [GO:0030307],
positive regulation of B cell proliferation [GO:0030890],
positive regulation of insulin secretion [GO:0032024],
response to estradiol [GO:0032355],
response to retinoic acid [GO:0032526],
response to progesterone [GO:0032570],
response to hydroperoxide [GO:0033194],
response to drug [GO:0042493],
negative regulation of apoptotic process [GO:0043066],
negative regulation of bone resorption [GO:0045779],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of vasoconstriction [GO:0045907],
B cell receptor signaling pathway [GO:0050853],
long term synaptic depression [GO:0060292],
response to interleukin-1 [GO:0070555],
apoptotic signaling pathway [GO:0097190],
positive regulation of cell proliferation [GO:0008284],
response to hormone [GO:0009725],

Molecular Function:
NAD+ nucleosidase activity [GO:0003953],
transferase activity [GO:0016740],
phosphorus-oxygen lyase activity [GO:0016849],
identical protein binding [GO:0042802],
NAD(P)+ nucleosidase activity [GO:0050135],
hydrolase activity [GO:0016787],
hydrolase activity, acting on glycosyl bonds [GO:0016798],

Cellular Component:
nucleus [GO:0005634],
plasma membrane [GO:0005886],
cell surface [GO:0009986],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
basolateral plasma membrane [GO:0016323],
secretory granule membrane [GO:0030667],
extracellular exosome [GO:0070062],
intracellular membrane-bounded organelle [GO:0043231],