ADAM11

ADAM metallopeptidase domain 11

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
integrin-mediated signaling pathway [GO:0007229],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
integrin binding [GO:0005178],
metallopeptidase activity [GO:0008237],
protein binding [GO:0005515],

Cellular Component:
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
membrane [GO:0016020],