ADA

adenosine deaminase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

GO terms:

Biological Process:
response to hypoxia [GO:0001666],
histamine secretion [GO:0001821],
trophectodermal cell differentiation [GO:0001829],
liver development [GO:0001889],
placenta development [GO:0001890],
germinal center B cell differentiation [GO:0002314],
positive regulation of germinal center formation [GO:0002636],
negative regulation of leukocyte migration [GO:0002686],
negative regulation of mature B cell apoptotic process [GO:0002906],
adenosine catabolic process [GO:0006154],
deoxyadenosine catabolic process [GO:0006157],
cell adhesion [GO:0007155],
aging [GO:0007568],
purine ribonucleoside monophosphate biosynthetic process [GO:0009168],
positive regulation of heart rate [GO:0010460],
positive regulation of B cell proliferation [GO:0030890],
purine nucleotide salvage [GO:0032261],
positive regulation of T cell differentiation in thymus [GO:0033089],
response to vitamin E [GO:0033197],
regulation of cell-cell adhesion mediated by integrin [GO:0033632],
T cell activation [GO:0042110],
negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323],
response to hydrogen peroxide [GO:0042542],
purine-containing compound salvage [GO:0043101],
hypoxanthine salvage [GO:0043103],
response to morphine [GO:0043278],
positive regulation of smooth muscle contraction [GO:0045987],
dATP catabolic process [GO:0046061],
inosine biosynthetic process [GO:0046103],
xanthine biosynthetic process [GO:0046111],
positive regulation of alpha-beta T cell differentiation [GO:0046638],
lung alveolus development [GO:0048286],
Peyer's patch development [GO:0048541],
embryonic digestive tract development [GO:0048566],
negative regulation of inflammatory response [GO:0050728],
positive regulation of calcium-mediated signaling [GO:0050850],
positive regulation of T cell receptor signaling pathway [GO:0050862],
negative regulation of adenosine receptor signaling pathway [GO:0060169],
negative regulation of penile erection [GO:0060407],
negative regulation of thymocyte apoptotic process [GO:0070244],
negative regulation of mucus secretion [GO:0070256],
in utero embryonic development [GO:0001701],
nucleotide metabolic process [GO:0009117],
lung development [GO:0030324],
negative regulation of apoptotic process [GO:0043066],
regulation of T cell differentiation [GO:0045580],
positive regulation of T cell differentiation [GO:0045582],
adenosine metabolic process [GO:0046085],
hypoxanthine biosynthetic process [GO:0046101],
positive regulation of T cell activation [GO:0050870],

Molecular Function:
purine nucleoside binding [GO:0001883],
adenosine deaminase activity [GO:0004000],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
hydrolase activity [GO:0016787],
deaminase activity [GO:0019239],
metal ion binding [GO:0046872],

Cellular Component:
extracellular space [GO:0005615],
lysosome [GO:0005764],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
external side of plasma membrane [GO:0009897],
cell surface [GO:0009986],
membrane [GO:0016020],
cell junction [GO:0030054],
dendrite cytoplasm [GO:0032839],
neuronal cell body [GO:0043025],
cytoplasmic vesicle lumen [GO:0060205],
cytoplasm [GO:0005737],
cytoplasmic vesicle [GO:0031410],