AASS
aminoadipate-semialdehyde synthase
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
lysine catabolic process [GO:0006554],
lysine biosynthetic process via aminoadipic acid [GO:0019878],
L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512],
oxidation-reduction process [GO:0055114],
generation of precursor metabolites and energy [GO:0006091],
metabolic process [GO:0008152],
L-lysine catabolic process [GO:0019477],
Molecular Function:
saccharopine dehydrogenase activity [GO:0004753],
saccharopine dehydrogenase (NADP+, L-lysine-forming) activity [GO:0047130],
saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity [GO:0047131],
catalytic activity [GO:0003824],
oxidoreductase activity [GO:0016491],
Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
intracellular membrane-bounded organelle [GO:0043231],