ACVR2B

activin A receptor type 2B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
gastrulation with mouth forming second [GO:0001702],
kidney development [GO:0001822],
lymphangiogenesis [GO:0001946],
blood vessel remodeling [GO:0001974],
regulation of transcription, DNA-templated [GO:0006355],
protein phosphorylation [GO:0006468],
signal transduction [GO:0007165],
transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178],
determination of left/right symmetry [GO:0007368],
mesoderm development [GO:0007498],
heart development [GO:0007507],
response to glucose [GO:0009749],
post-embryonic development [GO:0009791],
anterior/posterior pattern specification [GO:0009952],
insulin secretion [GO:0030073],
lung development [GO:0030324],
positive regulation of bone mineralization [GO:0030501],
BMP signaling pathway [GO:0030509],
pancreas development [GO:0031016],
activation of protein kinase activity [GO:0032147],
activin receptor signaling pathway [GO:0032924],
positive regulation of activin receptor signaling pathway [GO:0032927],
organ growth [GO:0035265],
odontogenesis of dentin-containing tooth [GO:0042475],
positive regulation of osteoblast differentiation [GO:0045669],
embryonic foregut morphogenesis [GO:0048617],
skeletal system morphogenesis [GO:0048705],
palate development [GO:0060021],
lymphatic endothelial cell differentiation [GO:0060836],
artery development [GO:0060840],
venous blood vessel development [GO:0060841],
retina vasculature development in camera-type eye [GO:0061298],
cellular response to growth factor stimulus [GO:0071363],
skeletal system development [GO:0001501],
pattern specification process [GO:0007389],
regulation of signal transduction [GO:0009966],
phosphorylation [GO:0016310],

Molecular Function:
protein serine/threonine kinase activity [GO:0004674],
protein serine/threonine/tyrosine kinase activity [GO:0004712],
protein binding [GO:0005515],
ATP binding [GO:0005524],
activin receptor activity, type II [GO:0016362],
activin-activated receptor activity [GO:0017002],
growth factor binding [GO:0019838],
metal ion binding [GO:0046872],
activin binding [GO:0048185],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
transmembrane receptor protein serine/threonine kinase activity [GO:0004675],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
inhibin binding [GO:0034711],
transforming growth factor beta binding [GO:0050431],

Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
macromolecular complex [GO:0032991],
receptor complex [GO:0043235],
activin receptor complex [GO:0048179],
membrane [GO:0016020],
integral component of membrane [GO:0016021],