actin related protein 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
establishment or maintenance of cell polarity [GO:0007163],
associative learning [GO:0008306],
asymmetric cell division [GO:0008356],
positive regulation of lamellipodium assembly [GO:0010592],
meiotic chromosome movement towards spindle pole [GO:0016344],
cytosolic transport [GO:0016482],
meiotic cytokinesis [GO:0033206],
Arp2/3 complex-mediated actin nucleation [GO:0034314],
response to immobilization stress [GO:0035902],
cellular response to trichostatin A [GO:0035984],
Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096],
neutrophil degranulation [GO:0043312],
response to ethanol [GO:0045471],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
ephrin receptor signaling pathway [GO:0048013],
spindle localization [GO:0051653],
cilium assembly [GO:0060271],
positive regulation of dendritic spine morphogenesis [GO:0061003],
membrane organization [GO:0061024],
cellular response to interferon-gamma [GO:0071346],
positive regulation of double-strand break repair via homologous recombination [GO:1905168],
regulation of double-strand break repair via nonhomologous end joining [GO:2001032],
actin filament organization [GO:0007015],
actin cytoskeleton organization [GO:0030036],
meiotic cell cycle [GO:0051321],

Molecular Function:
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
ATP binding [GO:0005524],
actin filament binding [GO:0051015],
nucleotide binding [GO:0000166],
actin binding [GO:0003779],
cytoskeletal protein binding [GO:0008092],

Cellular Component:
extracellular region [GO:0005576],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
Arp2/3 protein complex [GO:0005885],
focal adhesion [GO:0005925],
postsynaptic density [GO:0014069],
actin cytoskeleton [GO:0015629],
membrane [GO:0016020],
lamellipodium [GO:0030027],
actin cap [GO:0030478],
actin cortical patch [GO:0030479],
azurophil granule lumen [GO:0035578],
site of double-strand break [GO:0035861],
extracellular exosome [GO:0070062],
invadopodium [GO:0071437],
ficolin-1-rich granule lumen [GO:1904813],
cytoskeleton [GO:0005856],
cell cortex [GO:0005938],
cell projection [GO:0042995],
postsynapse [GO:0098794],