CBR3

carbonyl reductase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
xenobiotic metabolic process [GO:0006805],
phylloquinone catabolic process [GO:0042376],
cognition [GO:0050890],
oxidation-reduction process [GO:0055114],

Molecular Function:
3-keto sterol reductase activity [GO:0000253],
carbonyl reductase (NADPH) activity [GO:0004090],
protein binding [GO:0005515],
NADPH binding [GO:0070402],
oxidoreductase activity [GO:0016491],

Cellular Component:
extracellular space [GO:0005615],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
cytoplasm [GO:0005737],