ACTL6A

actin like 6A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
blastocyst formation [GO:0001825],
neural retina development [GO:0003407],
DNA repair [GO:0006281],
DNA recombination [GO:0006310],
chromatin remodeling [GO:0006338],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
signal transduction [GO:0007165],
nervous system development [GO:0007399],
protein deubiquitination [GO:0016579],
spinal cord development [GO:0021510],
regulation of growth [GO:0040008],
ATP-dependent chromatin remodeling [GO:0043044],
histone H4 acetylation [GO:0043967],
histone H2A acetylation [GO:0043968],
positive regulation of nucleic acid-templated transcription [GO:1903508],
chromatin organization [GO:0006325],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
chromatin binding [GO:0003682],
transcription coactivator activity [GO:0003713],
protein binding [GO:0005515],
nucleosomal DNA binding [GO:0031492],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
plasma membrane [GO:0005886],
SWI/SNF complex [GO:0016514],
Ino80 complex [GO:0031011],
macromolecular complex [GO:0032991],
NuA4 histone acetyltransferase complex [GO:0035267],
npBAF complex [GO:0071564],
SWI/SNF superfamily-type complex [GO:0070603],