CAV2

caveolin 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30987592 MCF7 Breast Human YES
31148378 MRC-5 Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
negative regulation of endothelial cell proliferation [GO:0001937],
positive regulation of endothelial cell proliferation [GO:0001938],
vesicle fusion [GO:0006906],
mitochondrion organization [GO:0007005],
endoplasmic reticulum organization [GO:0007029],
regulation of mitotic nuclear division [GO:0007088],
insulin receptor signaling pathway [GO:0008286],
vesicle organization [GO:0016050],
receptor-mediated endocytosis of virus by host cell [GO:0019065],
cell differentiation [GO:0030154],
negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512],
positive regulation of MAPK cascade [GO:0043410],
positive regulation of GTPase activity [GO:0043547],
positive regulation by host of viral release from host cell [GO:0044791],
positive regulation by host of viral process [GO:0044794],
vesicle docking [GO:0048278],
skeletal muscle fiber development [GO:0048741],
regulation of cytosolic calcium ion concentration [GO:0051480],
positive regulation of dopamine receptor signaling pathway [GO:0060161],
caveola assembly [GO:0070836],
basement membrane organization [GO:0071711],
endocytosis [GO:0006897],
chemical synaptic transmission [GO:0007268],
negative regulation of cell proliferation [GO:0008285],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
positive regulation of protein localization to nucleus [GO:1900182],

Molecular Function:
protein binding [GO:0005515],
protein kinase binding [GO:0019901],
protein binding, bridging [GO:0030674],
protein homodimerization activity [GO:0042803],
protein heterodimerization activity [GO:0046982],
binding, bridging [GO:0060090],
scaffold protein binding [GO:0097110],
SNARE binding [GO:0000149],
syntaxin binding [GO:0019905],
mitogen-activated protein kinase kinase kinase binding [GO:0031435],
D1 dopamine receptor binding [GO:0031748],
phosphoprotein binding [GO:0051219],

Cellular Component:
Golgi membrane [GO:0000139],
acrosomal membrane [GO:0002080],
caveolar macromolecular signaling complex [GO:0002095],
nucleus [GO:0005634],
Golgi apparatus [GO:0005794],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
caveola [GO:0005901],
focal adhesion [GO:0005925],
transport vesicle [GO:0030133],
extrinsic component of cytoplasmic side of plasma membrane [GO:0031234],
cytoplasmic vesicle [GO:0031410],
macromolecular complex [GO:0032991],
sarcolemma [GO:0042383],
membrane raft [GO:0045121],
perinuclear region of cytoplasm [GO:0048471],
nuclear envelope [GO:0005635],
nuclear inner membrane [GO:0005637],
cytoplasm [GO:0005737],
endoplasmic reticulum [GO:0005783],
lipid particle [GO:0005811],
cytosol [GO:0005829],
cell surface [GO:0009986],
membrane [GO:0016020],