CASQ1

calsequestrin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
endoplasmic reticulum organization [GO:0007029],
skeletal muscle tissue development [GO:0007519],
response to heat [GO:0009408],
response to organic substance [GO:0010033],
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809],
response to denervation involved in regulation of muscle adaptation [GO:0014894],
ion transmembrane transport [GO:0034220],
sarcomere organization [GO:0045214],
protein polymerization [GO:0051258],
regulation of release of sequestered calcium ion into cytosol [GO:0051279],
positive regulation of release of sequestered calcium ion into cytosol [GO:0051281],
positive regulation of store-operated calcium channel activity [GO:1901341],
regulation of cardiac conduction [GO:1903779],
regulation of store-operated calcium entry [GO:2001256],
regulation of muscle contraction [GO:0006937],
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880],
regulation of sequestering of calcium ion [GO:0051282],

Molecular Function:
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
identical protein binding [GO:0042802],
metal ion binding [GO:0046872],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
endoplasmic reticulum [GO:0005783],
smooth endoplasmic reticulum [GO:0005790],
Golgi apparatus [GO:0005794],
terminal cisterna lumen [GO:0014804],
sarcoplasmic reticulum [GO:0016529],
Z disc [GO:0030018],
T-tubule [GO:0030315],
sarcoplasmic reticulum membrane [GO:0033017],
sarcoplasmic reticulum lumen [GO:0033018],
cytoplasm [GO:0005737],
terminal cisterna [GO:0014802],
membrane [GO:0016020],
myofibril [GO:0030016],
I band [GO:0031674],
sarcolemma [GO:0042383],
intracellular membrane-bounded organelle [GO:0043231],