actin alpha cardiac muscle 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31534052 Kidney Mouse YES
31945125 Primary astrocytes derived from brain Human YES
31915373 Hheart_LA_VS healthy Cardiomyocyte Human NO
31915373 Hheart_LV_VS healthy Cardiomyocyte Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
33296652 heart heart Human NO

GO terms:

Biological Process:
actin filament organization [GO:0007015],
positive regulation of gene expression [GO:0010628],
actin filament-based movement [GO:0030048],
muscle filament sliding [GO:0030049],
skeletal muscle thin filament assembly [GO:0030240],
actomyosin structure organization [GO:0031032],
actin-myosin filament sliding [GO:0033275],
negative regulation of apoptotic process [GO:0043066],
response to ethanol [GO:0045471],
cardiac myofibril assembly [GO:0055003],
cardiac muscle tissue morphogenesis [GO:0055008],
heart contraction [GO:0060047],
cardiac muscle contraction [GO:0060048],
mesenchyme migration [GO:0090131],
actin-mediated cell contraction [GO:0070252],

Molecular Function:
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
myosin binding [GO:0017022],
nucleotide binding [GO:0000166],
protein binding [GO:0005515],

Cellular Component:
extracellular space [GO:0005615],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
dynactin complex [GO:0005869],
actin filament [GO:0005884],
focal adhesion [GO:0005925],
actin cytoskeleton [GO:0015629],
membrane [GO:0016020],
sarcomere [GO:0030017],
lamellipodium [GO:0030027],
filopodium [GO:0030175],
I band [GO:0031674],
actomyosin, actin portion [GO:0042643],
cell body [GO:0044297],
extracellular exosome [GO:0070062],
blood microparticle [GO:0072562],
glutamatergic synapse [GO:0098978],
cytoskeleton [GO:0005856],
synapse [GO:0045202],