Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
32158519 HUVEC Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES

GO terms:

Biological Process:
antigen processing and presentation of peptide antigen via MHC class I [GO:0002474],
protein folding [GO:0006457],
aging [GO:0007568],
protein secretion [GO:0009306],
viral process [GO:0016032],
antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886],
endoplasmic reticulum unfolded protein response [GO:0030968],
protein folding in endoplasmic reticulum [GO:0034975],
synaptic vesicle endocytosis [GO:0048488],
interleukin-27-mediated signaling pathway [GO:0070106],
interleukin-35-mediated signaling pathway [GO:0070757],
clathrin-dependent endocytosis [GO:0072583],

Molecular Function:
RNA binding [GO:0003723],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
carbohydrate binding [GO:0030246],
apolipoprotein binding [GO:0034185],
ionotropic glutamate receptor binding [GO:0035255],
unfolded protein binding [GO:0051082],
metal ion binding [GO:0046872],

Cellular Component:
endoplasmic reticulum [GO:0005783],
endoplasmic reticulum lumen [GO:0005788],
endoplasmic reticulum membrane [GO:0005789],
smooth endoplasmic reticulum [GO:0005790],
rough endoplasmic reticulum [GO:0005791],
ribosome [GO:0005840],
membrane [GO:0016020],
axon [GO:0030424],
dendrite cytoplasm [GO:0032839],
macromolecular complex [GO:0032991],
melanosome [GO:0042470],
neuronal cell body [GO:0043025],
dendritic spine [GO:0043197],
ER-mitochondrion membrane contact site [GO:0044233],
endoplasmic reticulum quality control compartment [GO:0044322],
extracellular exosome [GO:0070062],
integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556],
glutamatergic synapse [GO:0098978],
integral component of postsynaptic membrane [GO:0099055],
integral component of presynaptic active zone membrane [GO:0099059],
cytoplasm [GO:0005737],
integral component of membrane [GO:0016021],
myelin sheath [GO:0043209],