calcium/calmodulin dependent protein kinase IV

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
adaptive immune response [GO:0002250],
myeloid dendritic cell cytokine production [GO:0002372],
protein phosphorylation [GO:0006468],
inflammatory response [GO:0006954],
signal transduction [GO:0007165],
long-term memory [GO:0007616],
peptidyl-serine phosphorylation [GO:0018105],
regulation of T cell differentiation in thymus [GO:0033081],
intracellular signal transduction [GO:0035556],
myeloid dendritic cell differentiation [GO:0043011],
regulation of osteoclast differentiation [GO:0045670],
positive regulation of transcription, DNA-templated [GO:0045893],
protein autophosphorylation [GO:0046777],
immune system process [GO:0002376],
nucleocytoplasmic transport [GO:0006913],
neuron-neuron synaptic transmission [GO:0007270],
phosphorylation [GO:0016310],
positive regulation of protein export from nucleus [GO:0046827],
postsynapse to nucleus signaling pathway [GO:0099527],

Molecular Function:
calmodulin-dependent protein kinase activity [GO:0004683],
calmodulin binding [GO:0005516],
ATP binding [GO:0005524],
calcium-dependent protein serine/threonine kinase activity [GO:0009931],
nucleotide binding [GO:0000166],
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
kinase activity [GO:0016301],
transferase activity [GO:0016740],

Cellular Component:
fibrillar center [GO:0001650],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
extracellular exosome [GO:0070062],
postsynapse [GO:0098794],
glutamatergic synapse [GO:0098978],
cytosol [GO:0005829],
GABA-ergic synapse [GO:0098982],