CALM1

calmodulin 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
32408024 HeLa Human No

GO terms:

Biological Process:
MAPK cascade [GO:0000165],
microtubule cytoskeleton organization [GO:0000226],
regulation of heart rate [GO:0002027],
platelet degranulation [GO:0002576],
detection of calcium ion [GO:0005513],
glycogen catabolic process [GO:0005980],
muscle contraction [GO:0006936],
G-protein coupled receptor signaling pathway [GO:0007186],
Wnt signaling pathway, calcium modulating pathway [GO:0007223],
positive regulation of peptidyl-threonine phosphorylation [GO:0010800],
negative regulation of peptidyl-threonine phosphorylation [GO:0010801],
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880],
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881],
viral process [GO:0016032],
calcium-mediated signaling [GO:0019722],
substantia nigra development [GO:0021762],
regulation of rhodopsin mediated signaling pathway [GO:0022400],
positive regulation of protein autophosphorylation [GO:0031954],
regulation of cytokinesis [GO:0032465],
positive regulation of phosphoprotein phosphatase activity [GO:0032516],
positive regulation of protein dephosphorylation [GO:0035307],
Fc-epsilon receptor signaling pathway [GO:0038095],
inositol phosphate metabolic process [GO:0043647],
regulation of nitric-oxide synthase activity [GO:0050999],
positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343],
response to calcium ion [GO:0051592],
regulation of cardiac muscle contraction [GO:0055117],
regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314],
negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315],
positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316],
positive regulation of protein serine/threonine kinase activity [GO:0071902],
regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844],
G2/M transition of mitotic cell cycle [GO:0000086],
positive regulation of DNA binding [GO:0043388],

Molecular Function:
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
adenylate cyclase binding [GO:0008179],
adenylate cyclase activator activity [GO:0010856],
calcium channel inhibitor activity [GO:0019855],
protein kinase binding [GO:0019901],
protein domain specific binding [GO:0019904],
enzyme regulator activity [GO:0030234],
titin binding [GO:0031432],
N-terminal myristoylation domain binding [GO:0031997],
protein serine/threonine kinase activator activity [GO:0043539],
ion channel binding [GO:0044325],
protein phosphatase activator activity [GO:0072542],
disordered domain specific binding [GO:0097718],
nitric-oxide synthase regulator activity [GO:0030235],
type 3 metabotropic glutamate receptor binding [GO:0031800],
phosphatidylinositol 3-kinase binding [GO:0043548],
protein N-terminus binding [GO:0047485],
calcium-dependent protein binding [GO:0048306],
nitric-oxide synthase binding [GO:0050998],

Cellular Component:
spindle pole [GO:0000922],
extracellular region [GO:0005576],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
centrosome [GO:0005813],
cytosol [GO:0005829],
spindle microtubule [GO:0005876],
plasma membrane [GO:0005886],
sarcomere [GO:0030017],
vesicle [GO:0031982],
macromolecular complex [GO:0032991],
calcium channel complex [GO:0034704],
catalytic complex [GO:1902494],
voltage-gated potassium channel complex [GO:0008076],
growth cone [GO:0030426],
synaptic vesicle membrane [GO:0030672],
mitochondrial membrane [GO:0031966],
neuron projection [GO:0043005],
myelin sheath [GO:0043209],