acyl-CoA synthetase short chain family member 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
ketone body biosynthetic process [GO:0046951],
biological_process [GO:0008150],

Molecular Function:
acetate-CoA ligase activity [GO:0003987],
ATP binding [GO:0005524],
butyrate-CoA ligase activity [GO:0047760],
propionate-CoA ligase activity [GO:0050218],
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
ligase activity [GO:0016874],

Cellular Component:
mitochondrial matrix [GO:0005759],
mitochondrion [GO:0005739],