acyl-CoA synthetase short chain family member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
ethanol oxidation [GO:0006069],
lipid biosynthetic process [GO:0008610],
acetate biosynthetic process [GO:0019413],
acetyl-CoA biosynthetic process from acetate [GO:0019427],
propionate biosynthetic process [GO:0019542],
acetyl-CoA biosynthetic process [GO:0006085],

Molecular Function:
acetate-CoA ligase activity [GO:0003987],
ATP binding [GO:0005524],
AMP binding [GO:0016208],
propionate-CoA ligase activity [GO:0050218],
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
ligase activity [GO:0016874],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrial matrix [GO:0005759],
cytosol [GO:0005829],
intracellular membrane-bounded organelle [GO:0043231],