acyl-CoA synthetase medium chain family member 4

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA52 Skin, Lung Human YES
30988157 IMR-90 Human YES

GO terms:

Biological Process:
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],
fatty acid biosynthetic process [GO:0006633],
acyl-CoA metabolic process [GO:0006637],

Molecular Function:
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
acyl-CoA ligase activity [GO:0003996],
fatty-acyl-CoA synthase activity [GO:0004321],
ATP binding [GO:0005524],
fatty acid ligase activity [GO:0015645],
ligase activity [GO:0016874],
metal ion binding [GO:0046872],
butyrate-CoA ligase activity [GO:0047760],
decanoate--CoA ligase activity [GO:0102391],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],