ACSL6

acyl-CoA synthetase long chain family member 6

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
very long-chain fatty acid metabolic process [GO:0000038],
long-chain fatty acid metabolic process [GO:0001676],
acyl-CoA metabolic process [GO:0006637],
lipid biosynthetic process [GO:0008610],
long-chain fatty-acyl-CoA biosynthetic process [GO:0035338],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],
neuroblast proliferation [GO:0007405],
phospholipid biosynthetic process [GO:0008654],
positive regulation of plasma membrane long-chain fatty acid transport [GO:0010747],
positive regulation of neuron projection development [GO:0010976],
fatty acid transport [GO:0015908],
triglyceride biosynthetic process [GO:0019432],

Molecular Function:
acyl-CoA ligase activity [GO:0003996],
long-chain fatty acid-CoA ligase activity [GO:0004467],
ATP binding [GO:0005524],
protein homodimerization activity [GO:0042803],
arachidonate-CoA ligase activity [GO:0047676],
decanoate--CoA ligase activity [GO:0102391],
nucleotide binding [GO:0000166],
catalytic activity [GO:0003824],
protein binding [GO:0005515],
ligase activity [GO:0016874],
enzyme binding [GO:0019899],

Cellular Component:
mitochondrial outer membrane [GO:0005741],
peroxisomal membrane [GO:0005778],
endoplasmic reticulum [GO:0005783],
endoplasmic reticulum membrane [GO:0005789],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
nucleus [GO:0005634],
mitochondrion [GO:0005739],
peroxisome [GO:0005777],
intracellular membrane-bounded organelle [GO:0043231],