zinc finger RANBP2-type containing 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA283 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
DNA strand renaturation [GO:0000733],
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],
response to UV [GO:0009411],
replication fork processing [GO:0031297],
DNA duplex unwinding [GO:0032508],
DNA rewinding [GO:0036292],
negative regulation of DNA recombination [GO:0045910],
replication fork protection [GO:0048478],
nucleic acid phosphodiester bond hydrolysis [GO:0090305],
metabolic process [GO:0008152],

Molecular Function:
DNA helicase activity [GO:0003678],
endodeoxyribonuclease activity [GO:0004520],
protein binding [GO:0005515],
ATP binding [GO:0005524],
DNA-dependent ATPase activity [GO:0008094],
annealing helicase activity [GO:0036310],
metal ion binding [GO:0046872],
K63-linked polyubiquitin binding [GO:0070530],
nucleotide binding [GO:0000166],
nucleic acid binding [GO:0003676],
catalytic activity [GO:0003824],
helicase activity [GO:0004386],
nuclease activity [GO:0004518],
endonuclease activity [GO:0004519],
hydrolase activity [GO:0016787],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
nuclear replication fork [GO:0043596],
chromosome [GO:0005694],