zinc finger FYVE-type containing 16

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
protein targeting to lysosome [GO:0006622],
signal transduction [GO:0007165],
vesicle organization [GO:0016050],
endosomal transport [GO:0016197],
regulation of endocytosis [GO:0030100],
BMP signaling pathway [GO:0030509],

Molecular Function:
protein binding [GO:0005515],
1-phosphatidylinositol binding [GO:0005545],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
metal ion binding [GO:0046872],

Cellular Component:
early endosome [GO:0005769],
cytosol [GO:0005829],
early endosome membrane [GO:0031901],
intracellular membrane-bounded organelle [GO:0043231],
cytoplasm [GO:0005737],
endosome [GO:0005768],
membrane [GO:0016020],