zinc finger FYVE-type containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cellular response to starvation [GO:0009267],
negative regulation of phosphatase activity [GO:0010923],
macroautophagy [GO:0016236],

Molecular Function:
protein binding [GO:0005515],
1-phosphatidylinositol binding [GO:0005545],
phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547],
zinc ion binding [GO:0008270],
phosphatidylinositol-3-phosphate binding [GO:0032266],
phosphatidylinositol-3,4-bisphosphate binding [GO:0043325],
metal ion binding [GO:0046872],

Cellular Component:
pre-autophagosomal structure [GO:0000407],
mitochondrion [GO:0005739],
autophagosome [GO:0005776],
endoplasmic reticulum [GO:0005783],
endoplasmic reticulum membrane [GO:0005789],
Golgi apparatus [GO:0005794],
Golgi stack [GO:0005795],
lipid particle [GO:0005811],
membrane [GO:0016020],
ER-mitochondrion membrane contact site [GO:0044233],
perinuclear region of cytoplasm [GO:0048471],
extrinsic component of omegasome membrane [GO:0097629],
omegasome [GO:1990462],