ZFPM2

zinc finger protein, FOG family member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
vasculogenesis [GO:0001570],
in utero embryonic development [GO:0001701],
outflow tract septum morphogenesis [GO:0003148],
outflow tract morphogenesis [GO:0003151],
atrioventricular valve morphogenesis [GO:0003181],
mitral valve formation [GO:0003192],
tricuspid valve formation [GO:0003195],
right ventricular cardiac muscle tissue morphogenesis [GO:0003221],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
heart development [GO:0007507],
cell differentiation [GO:0030154],
lung development [GO:0030324],
negative regulation of fat cell differentiation [GO:0045599],
negative regulation of transcription, DNA-templated [GO:0045892],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
embryonic organ development [GO:0048568],
cardiac muscle tissue development [GO:0048738],
cardiac muscle tissue morphogenesis [GO:0055008],
positive regulation of cardiac muscle cell proliferation [GO:0060045],
ventricular septum morphogenesis [GO:0060412],
negative regulation of cell death [GO:0060548],
vasculogenesis involved in coronary vascular morphogenesis [GO:0060979],
positive regulation of male gonad development [GO:2000020],
negative regulation of female gonad development [GO:2000195],
gonadal mesoderm development [GO:0007506],
blood coagulation [GO:0007596],

Molecular Function:
RNA polymerase II transcription factor binding [GO:0001085],
nucleic acid binding [GO:0003676],
DNA binding [GO:0003677],
transcription corepressor activity [GO:0003714],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
metal ion binding [GO:0046872],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
transcription coactivator activity [GO:0003713],
zinc ion binding [GO:0008270],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
nuclear chromatin [GO:0000790],