YY1

YY1 transcription factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
18558095 293T, NCI-H460 Human NO

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
double-strand break repair via homologous recombination [GO:0000724],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
RNA localization [GO:0006403],
cellular response to DNA damage stimulus [GO:0006974],
spermatogenesis [GO:0007283],
anterior/posterior pattern specification [GO:0009952],
response to UV-C [GO:0010225],
gene expression [GO:0010467],
negative regulation of gene expression [GO:0010629],
protein deubiquitination [GO:0016579],
cell differentiation [GO:0030154],
negative regulation of interferon-beta production [GO:0032688],
cellular response to UV [GO:0034644],
response to prostaglandin F [GO:0034696],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
camera-type eye morphogenesis [GO:0048593],
chromosome organization [GO:0051276],
negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052],
cellular response to interleukin-1 [GO:0071347],
negative regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902894],
DNA repair [GO:0006281],
DNA recombination [GO:0006310],
regulation of transcription, DNA-templated [GO:0006355],
positive regulation of gene expression [GO:0010628],

Molecular Function:
four-way junction DNA binding [GO:0000400],
transcription regulatory region sequence-specific DNA binding [GO:0000976],
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
core promoter proximal region sequence-specific DNA binding [GO:0000987],
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001227],
DNA binding [GO:0003677],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
transcription coactivator activity [GO:0003713],
transcription corepressor activity [GO:0003714],
RNA binding [GO:0003723],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
sequence-specific DNA binding [GO:0043565],
SMAD binding [GO:0046332],
nucleic acid binding [GO:0003676],
metal ion binding [GO:0046872],

Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcription factor complex [GO:0005667],
cytoplasm [GO:0005737],
nuclear matrix [GO:0016363],
Ino80 complex [GO:0031011],
PcG protein complex [GO:0031519],
chromatin silencing complex [GO:0005677],