tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
25412315 A172, MEF Human, mouse NO
31222857 HEp-2,SNU899 Human NO

GO terms:

Biological Process:
angiogenesis [GO:0001525],
respiratory system process [GO:0003016],
protein phosphorylation [GO:0006468],
protein targeting [GO:0006605],
signal transduction [GO:0007165],
synaptic target recognition [GO:0008039],
cytokine-mediated signaling pathway [GO:0019221],
platelet activation [GO:0030168],
lung development [GO:0030324],
tube formation [GO:0035148],
negative regulation of apoptotic process [GO:0043066],
regulation of mRNA stability [GO:0043488],
establishment of Golgi localization [GO:0051683],
membrane organization [GO:0061024],
ERK1 and ERK2 cascade [GO:0070371],
regulation of ERK1 and ERK2 cascade [GO:0070372],
regulation of synapse maturation [GO:0090128],
Golgi reassembly [GO:0090168],
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740],
histamine secretion by mast cell [GO:0002553],
protein targeting to mitochondrion [GO:0006626],
regulation of cell death [GO:0010941],
response to drug [GO:0042493],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
protein kinase binding [GO:0019901],
protein domain specific binding [GO:0019904],
ubiquitin protein ligase binding [GO:0031625],
identical protein binding [GO:0042802],
ion channel binding [GO:0044325],
cadherin binding [GO:0045296],
RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977],
macromolecular complex binding [GO:0044877],

Cellular Component:
extracellular space [GO:0005615],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
focal adhesion [GO:0005925],
vesicle [GO:0031982],
melanosome [GO:0042470],
extracellular exosome [GO:0070062],
blood microparticle [GO:0072562],
glutamatergic synapse [GO:0098978],
postsynaptic density [GO:0014069],
cell leading edge [GO:0031252],
macromolecular complex [GO:0032991],
perinuclear region of cytoplasm [GO:0048471],