WWC1

WW and C2 domain containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
positive regulation of transcription of Notch receptor target [GO:0007221],
cell migration [GO:0016477],
establishment of cell polarity [GO:0030010],
regulation of intracellular transport [GO:0032386],
hippo signaling [GO:0035329],
regulation of hippo signaling [GO:0035330],
negative regulation of hippo signaling [GO:0035331],
positive regulation of MAPK cascade [GO:0043410],
negative regulation of organ growth [GO:0046621],

Molecular Function:
transcription coactivator activity [GO:0003713],
protein binding [GO:0005515],
kinase binding [GO:0019900],
binding, bridging [GO:0060090],
protein binding, bridging [GO:0030674],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
ruffle membrane [GO:0032587],
macromolecular complex [GO:0032991],
perinuclear region of cytoplasm [GO:0048471],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cell projection [GO:0042995],