WNT7B

Wnt family member 7B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
25406515 BJ, WI-38 Human NO
30988157 IMR-90 Human YES
31964233 Primary mesenchymal stem cells derived from synovium Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
metanephros morphogenesis [GO:0003338],
activation of JUN kinase activity [GO:0007257],
Wnt signaling pathway [GO:0016055],
establishment or maintenance of polarity of embryonic epithelium [GO:0016332],
forebrain regionalization [GO:0021871],
central nervous system vasculogenesis [GO:0022009],
neuron differentiation [GO:0030182],
lung development [GO:0030324],
oxygen homeostasis [GO:0032364],
regulation of cell projection size [GO:0032536],
homeostatic process [GO:0042592],
cellular metabolic process [GO:0044237],
cell fate commitment [GO:0045165],
positive regulation of osteoblast differentiation [GO:0045669],
positive regulation of JNK cascade [GO:0046330],
fibroblast proliferation [GO:0048144],
embryonic organ development [GO:0048568],
neuron projection morphogenesis [GO:0048812],
synapse organization [GO:0050808],
response to glucocorticoid [GO:0051384],
canonical Wnt signaling pathway [GO:0060070],
lung morphogenesis [GO:0060425],
lung epithelium development [GO:0060428],
lobar bronchus development [GO:0060482],
trachea cartilage morphogenesis [GO:0060535],
developmental growth involved in morphogenesis [GO:0060560],
embryonic placenta morphogenesis [GO:0060669],
chorio-allantoic fusion [GO:0060710],
mammary gland epithelium development [GO:0061180],
lens fiber cell development [GO:0070307],
cellular response to retinoic acid [GO:0071300],
renal inner medulla development [GO:0072053],
renal outer medulla development [GO:0072054],
outer medullary collecting duct development [GO:0072060],
inner medullary collecting duct development [GO:0072061],
stem cell proliferation [GO:0072089],
metanephric collecting duct development [GO:0072205],
metanephric epithelium development [GO:0072207],
metanephric loop of Henle development [GO:0072236],
angiogenesis [GO:0001525],
vasculature development [GO:0001944],
multicellular organism development [GO:0007275],
positive regulation of cell proliferation [GO:0008284],
positive regulation of gene expression [GO:0010628],
cell proliferation in forebrain [GO:0021846],
neuron projection development [GO:0031175],
chemoattraction of dopaminergic neuron axon [GO:0036516],
odontogenesis of dentin-containing tooth [GO:0042475],
negative regulation of smoothened signaling pathway [GO:0045879],
stem cell development [GO:0048864],
negative regulation of neurogenesis [GO:0050768],
smooth muscle cell differentiation [GO:0051145],
anatomical structure regression [GO:0060033],
lung-associated mesenchyme development [GO:0060484],
apoptotic process involved in patterning of blood vessels [GO:1902262],
planar cell polarity pathway involved in axon guidance [GO:1904938],

Molecular Function:
frizzled binding [GO:0005109],
cytokine activity [GO:0005125],
protein binding [GO:0005515],
receptor agonist activity [GO:0048018],
receptor binding [GO:0005102],
chemoattractant activity involved in axon guidance [GO:1902379],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
endoplasmic reticulum lumen [GO:0005788],
Golgi lumen [GO:0005796],
plasma membrane [GO:0005886],
endocytic vesicle membrane [GO:0030666],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
cell surface [GO:0009986],