VPS53

VPS53 subunit of GARP complex

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA55 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
lysosomal transport [GO:0007041],
protein transport [GO:0015031],
endocytic recycling [GO:0032456],
retrograde transport, endosome to Golgi [GO:0042147],

Molecular Function:
protein binding [GO:0005515],

Cellular Component:
GARP complex [GO:0000938],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
endosome membrane [GO:0010008],
membrane [GO:0016020],
trans-Golgi network membrane [GO:0032588],
perinuclear region of cytoplasm [GO:0048471],
recycling endosome [GO:0055037],
EARP complex [GO:1990745],
endosome [GO:0005768],
trans-Golgi network [GO:0005802],