VEGFC

vascular endothelial growth factor C

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
response to hypoxia [GO:0001666],
positive regulation of protein phosphorylation [GO:0001934],
positive regulation of endothelial cell proliferation [GO:0001938],
sprouting angiogenesis [GO:0002040],
positive regulation of neuroblast proliferation [GO:0002052],
platelet degranulation [GO:0002576],
substrate-dependent cell migration [GO:0006929],
signal transduction [GO:0007165],
positive regulation of cell proliferation [GO:0008284],
animal organ morphogenesis [GO:0009887],
morphogenesis of embryonic epithelium [GO:0016331],
regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947],
positive regulation of protein autophosphorylation [GO:0031954],
vascular endothelial growth factor signaling pathway [GO:0038084],
response to drug [GO:0042493],
positive regulation of blood vessel endothelial cell migration [GO:0043536],
negative regulation of osteoblast differentiation [GO:0045668],
positive regulation of angiogenesis [GO:0045766],
negative regulation of blood pressure [GO:0045776],
positive regulation of protein kinase activity [GO:0045860],
vascular endothelial growth factor receptor signaling pathway [GO:0048010],
positive regulation of protein secretion [GO:0050714],
positive chemotaxis [GO:0050918],
induction of positive chemotaxis [GO:0050930],
positive regulation of cell division [GO:0051781],
positive regulation of mast cell chemotaxis [GO:0060754],
positive regulation of lymphangiogenesis [GO:1901492],
positive regulation of mesenchymal stem cell proliferation [GO:1902462],
cellular response to leukemia inhibitory factor [GO:1990830],
positive regulation of cell-matrix adhesion [GO:0001954],
multicellular organism development [GO:0007275],
negative regulation of cell proliferation [GO:0008285],
cell differentiation [GO:0030154],
positive regulation of cell migration [GO:0030335],
positive regulation of epithelial cell proliferation [GO:0050679],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],

Molecular Function:
vascular endothelial growth factor receptor binding [GO:0005172],
protein binding [GO:0005515],
growth factor activity [GO:0008083],
chemoattractant activity [GO:0042056],
vascular endothelial growth factor receptor 3 binding [GO:0043185],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
membrane [GO:0016020],
platelet alpha granule lumen [GO:0031093],