VCAM1
vascular cell adhesion molecule 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 24960204 | Primary fibroblasts derived from ear | Mouse | NO | |
| 31543366 | WA09 | Brain | Human, mouse | YES |
| 31581517 | Primary cells derived form heart | Pig | NO | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945054 | IMR-90 | Human | YES | |
| 32029712 | Primary synovial fibroblast | Human | YES | |
GO terms:
Biological Process:
cell adhesion [GO:0007155],
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157],
leukocyte cell-cell adhesion [GO:0007159],
cell-matrix adhesion [GO:0007160],
amine metabolic process [GO:0009308],
cytokine-mediated signaling pathway [GO:0019221],
membrane to membrane docking [GO:0022614],
B cell differentiation [GO:0030183],
extracellular matrix organization [GO:0030198],
heterotypic cell-cell adhesion [GO:0034113],
calcium-mediated signaling using intracellular calcium source [GO:0035584],
positive regulation of T cell proliferation [GO:0042102],
regulation of immune response [GO:0050776],
leukocyte tethering or rolling [GO:0050901],
oxidation-reduction process [GO:0055114],
interferon-gamma-mediated signaling pathway [GO:0060333],
cellular response to beta-amyloid [GO:1904646],
heart development [GO:0007507],
viral process [GO:0016032],
cell chemotaxis [GO:0060326],
innervation [GO:0060384],
embryonic placenta morphogenesis [GO:0060669],
chorio-allantoic fusion [GO:0060710],
cardiac neuron differentiation [GO:0060945],
visceral serous pericardium development [GO:0061032],
cellular response to glucose stimulus [GO:0071333],
cell-cell adhesion [GO:0098609],
Molecular Function:
integrin binding [GO:0005178],
primary amine oxidase activity [GO:0008131],
cell adhesion molecule binding [GO:0050839],
Cellular Component:
podosome [GO:0002102],
extracellular space [GO:0005615],
early endosome [GO:0005769],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
microvillus [GO:0005902],
external side of plasma membrane [GO:0009897],
cell surface [GO:0009986],
filopodium [GO:0030175],
apical part of cell [GO:0045177],
extracellular exosome [GO:0070062],
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
anchored component of membrane [GO:0031225],
sarcolemma [GO:0042383],
cell periphery [GO:0071944],