VCAM1

vascular cell adhesion molecule 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
24960204 Primary fibroblasts derived from ear Mouse NO
31543366 WA09 Brain Human, mouse YES
31581517 Primary cells derived form heart Pig NO
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
cell adhesion [GO:0007155],
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157],
leukocyte cell-cell adhesion [GO:0007159],
cell-matrix adhesion [GO:0007160],
amine metabolic process [GO:0009308],
cytokine-mediated signaling pathway [GO:0019221],
membrane to membrane docking [GO:0022614],
B cell differentiation [GO:0030183],
extracellular matrix organization [GO:0030198],
heterotypic cell-cell adhesion [GO:0034113],
calcium-mediated signaling using intracellular calcium source [GO:0035584],
positive regulation of T cell proliferation [GO:0042102],
regulation of immune response [GO:0050776],
leukocyte tethering or rolling [GO:0050901],
oxidation-reduction process [GO:0055114],
interferon-gamma-mediated signaling pathway [GO:0060333],
cellular response to beta-amyloid [GO:1904646],
heart development [GO:0007507],
viral process [GO:0016032],
cell chemotaxis [GO:0060326],
innervation [GO:0060384],
embryonic placenta morphogenesis [GO:0060669],
chorio-allantoic fusion [GO:0060710],
cardiac neuron differentiation [GO:0060945],
visceral serous pericardium development [GO:0061032],
cellular response to glucose stimulus [GO:0071333],
cell-cell adhesion [GO:0098609],

Molecular Function:
integrin binding [GO:0005178],
primary amine oxidase activity [GO:0008131],
cell adhesion molecule binding [GO:0050839],

Cellular Component:
podosome [GO:0002102],
extracellular space [GO:0005615],
early endosome [GO:0005769],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
microvillus [GO:0005902],
external side of plasma membrane [GO:0009897],
cell surface [GO:0009986],
filopodium [GO:0030175],
apical part of cell [GO:0045177],
extracellular exosome [GO:0070062],
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
anchored component of membrane [GO:0031225],
sarcolemma [GO:0042383],
cell periphery [GO:0071944],