UV radiation resistance associated

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
DNA repair [GO:0006281],
retrograde vesicle-mediated transport, Golgi to ER [GO:0006890],
autophagy [GO:0006914],
spindle organization [GO:0007051],
chromosome segregation [GO:0007059],
centrosome cycle [GO:0007098],
regulation of cytokinesis [GO:0032465],
receptor catabolic process [GO:0032801],
SNARE complex assembly [GO:0035493],
viral entry into host cell [GO:0046718],
maintenance of Golgi location [GO:0051684],
regulation of protein serine/threonine kinase activity [GO:0071900],
multivesicular body sorting pathway [GO:0071985],
autophagosome maturation [GO:0097352],
double-strand break repair via classical nonhomologous end joining [GO:0097680],
positive regulation of autophagosome maturation [GO:1901098],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
SNARE binding [GO:0000149],
protein binding [GO:0005515],
SH3 domain binding [GO:0017124],

Cellular Component:
lytic vacuole [GO:0000323],
autophagosome membrane [GO:0000421],
chromosome, centromeric region [GO:0000775],
cytoplasm [GO:0005737],
lysosome [GO:0005764],
endosome [GO:0005768],
early endosome [GO:0005769],
late endosome [GO:0005770],
endoplasmic reticulum [GO:0005783],
centrosome [GO:0005813],
midbody [GO:0030496],
phagocytic vesicle [GO:0045335],
DNA-dependent protein kinase complex [GO:0070418],
chromosome [GO:0005694],
cytoplasmic vesicle [GO:0031410],
macromolecular complex [GO:0032991],