Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
positive regulation of cell-matrix adhesion [GO:0001954],
muscle contraction [GO:0006936],
muscle organ development [GO:0007517],
neuromuscular junction development [GO:0007528],
response to denervation involved in regulation of muscle adaptation [GO:0014894],
regulation of sodium ion transmembrane transporter activity [GO:2000649],
adult somatic muscle development [GO:0007527],

Molecular Function:
actin binding [GO:0003779],
integrin binding [GO:0005178],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
vinculin binding [GO:0017166],
protein kinase binding [GO:0019901],
actin filament binding [GO:0051015],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
dystrophin-associated glycoprotein complex [GO:0016010],
membrane [GO:0016020],
filopodium [GO:0030175],
growth cone [GO:0030426],
cortical actin cytoskeleton [GO:0030864],
filopodium membrane [GO:0031527],
neuromuscular junction [GO:0031594],
macromolecular complex [GO:0032991],
sarcolemma [GO:0042383],
postsynaptic membrane [GO:0045211],
extracellular exosome [GO:0070062],
contractile ring [GO:0070938],
synapse [GO:0045202],